## Abstract ## BACKGROUND Thymidine phosphorylase (TP) is identical to plateletβderived endothelial cell growth factor (PDECGF) and has angiogenic activity. Little is known about the significance of TP/PDECGF activity in patients with renal cell carcinoma (RCC). The authors examined the enzymatic
Thymidine phosphorylase/platelet-derived endothelial cell growth factor (PD-ECGF) associated with prognosis in renal cell carcinoma
β Scribed by Suzuki, K. ;Morita, T. ;Hashimoto, S. ;Tokue, A.
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 204 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0300-5623
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We have investigated the expression of platelet-derived endothelial-cell growth factorkhymidine phosphorylase (PD-ECGF/dThdPase) in human breast-cancer tissues by the immunocytochemical method using anti-PD-ECGF/ dThdPase monoclonal antibody. Out of I00 invasive-ductal-carcinoma tissue samples, 39 (
## BACKGROUND. Platelet-derived endothelial cell growth factor (PD-ECGF) is an angiogenic factor that has potent chemotactic activity for endothelial cells. Although it is expressed in the majority of colorectal tumors, and some reports suggest that its high expression is related to poor prognosis,