Thymidine catabolism and the reutilization of its degradative products in Tetrahymena pyriformis Metabolism of [2,6-14C2]thymidine and [2-14C]methylmalonic acid
✍ Scribed by Marilyn A. Niemann; John Berech Jr.
- Book ID
- 115747622
- Publisher
- Elsevier Science
- Year
- 1981
- Weight
- 372 KB
- Volume
- 652
- Category
- Article
- ISSN
- 0005-2787
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## Abstract A convenient method of preparing 2‐octyl (4‐amino‐3,5‐dichloro‐6‐fluoro‐2‐pyridinyloxy‐2,6‐^14^C)acetate from glutarimide‐2,6‐^14^C is described. The process includes a novel one‐step conversion of glutarimide‐2,6‐^14^C to pentachloropyridine‐2,6‐^14^C.
## Abstract D,L‐2,6‐Diaminopimelic‐(2‐^14^C) acid was prepared by alkylation of diethyl acetamidomalonate‐(2‐^14^C) with 5‐bromo‐N‐phthaloyl‐L‐norvaline methyl ester and hydrolysis of the condensation product. Depending on the alkylation conditions, partial or complete racemisation takes place and