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Thymic squamous cell carcinoma producing granulocyte colony-stimulating factor associated with a high serum level of interleukin 6

✍ Scribed by Eriko Ayabe; Kyoichi Kaira; Toshiaki Takahashi; Haruyasu Murakami; Asuka Tsuya; Yukiko Nakamura; Tateaki Naito; Masahiro Endo; Nobuyuki Yamamoto


Publisher
Springer
Year
2009
Tongue
English
Weight
327 KB
Volume
14
Category
Article
ISSN
1341-9625

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## BACKGROUND. Interleukin-2 (IL-2) and granulocyte-macrophageΟͺcolony stimulating factor (GM-CSF) are cytokines with nonoverlapping pleiotropic effects. In a prior Phase Ib study, this combination of agents exhibited antitumor effects in the lungs of four of eight patients with renal cell carcinoma