Bone marrow myeloid cell kinetics during treatment of small cell carcinoma of the lung with chemotherapy not associated and associated with granulocyte-macrophage colony-stimulating factor
โ Scribed by A. Riccardi; M. Danova; A. Paccagnella; M. Giordano; A. Favaretto; M. Panozzo; C. Ghiotto; S. Comis; M. Fiorentino; L. Chieco-Bianchi; E. Ascari
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 914 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0939-5555
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## BACKGROUND. We performed a Phase 1-11 trial to determine the maximum tolerated dose of carboplatin (CBDCA) with a fixed dose of VP-16 and granulocyte-colony stimulating factor (G-CSF) in small cell lung cancer (SCLC) patients. ## METHODS. Treatment consisted of a starting dose of CBDCA, 400
BACKGROUND. This Phase I study was designed to determine the toxicity and efficacy of a carboplatin and irinotecan (CPT-11) regimen with recombinant human granulocyte colony-stimulating factor (rhG-CSF) support for patients with advanced nonsmall cell lung carcinoma. ## METHODS. Treatment consist