Thymic involution
β Scribed by Paul W. Turke
- Book ID
- 104298794
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 72 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0167-5699
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π SIMILAR VOLUMES
The prognosis of acute lymphoblastic leukemia is affected adversely by T-cell markers on the malignant lymphoblasts. Direct involvement of the thymus has been assumed because of frequent mediastinal enlargement in these patients and the important role of the thymus in certain mouse leukemias. We rep
The thymus undergoes an age-dependent degenerative process which is mainly characterized by a progressive loss of lymphoid tissue. Thymic involution is particularly important in relation to immunosenescence and its various associated diseases; this fact has prompted many studies aimed at understandi
Age-related thymic involution in mammals is accompanied by decreased generation of naΓ―ve T cells without significant reduction in the number of peripheral T cells. This leads to inefficient immune responses and inadequate combating of infections and other challenges to the immune system in older mam