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Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis

✍ Scribed by Jörg J Goronzy; Cornelia M Weyand

Book ID
117786838
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
122 KB
Volume
22
Category
Article
ISSN
1471-4906

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Rheumatoid arthritis is a T cell-mediated autoimmune disease. The lack of knowledge of the involved target antigens severely hampers research on relevant T cells in patients. Here we describe the functional analysis of freshly isolated T cells from the peripheral blood and the site of the lesion (sy