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Thrombospondin-1 in the trabecular meshwork: localization in normal and glaucomatous eyes, and induction by TGF-β1 and dexamethasone in vitro

✍ Scribed by Cassandra Flügel-Koch; Andreas Ohlmann; Rudolf Fuchshofer; Ulrich Welge-Lüssen; Ernst R. Tamm

Book ID
116456047
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
717 KB
Volume
79
Category
Article
ISSN
0014-4835

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## Abstract The pathophysiological mechanisms involved in the failure of the trabecular meshwork (TM) to maintain normal levels of aqueous outflow in glaucoma are not yet understood. Aberrant activation of the transforming growth factor beta‐1 (TGF‐β1) pathway has been implicated in several degener