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Thrombin stimulation of Cl−/HCO3− exchange in human platelets

✍ Scribed by Oscar A. Gende

Book ID
116913136
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
331 KB
Volume
116
Category
Article
ISSN
0049-3848

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Thrombin-induced cytosolic alkalinizatio
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✍ Norbert Clemens; Winfried Siffert; Peter Scheid 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 667 KB

We have estimated the changes in cytosolic pH (pHi) that occur when human platelets are stimulated by thrombin. Changes in pHi were estimated (i) from the H + effiux across the plasma membrane using an extracellular pH electrode and (ii) using an intracellular pH-sensitive fluorescent dye (BCECF). S