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Sequential sodium-proton exchange in thrombin-induced human platelets

โœ Scribed by Theresa A. Davies; Eva Katona; Vasili Vasilescu; Edward J. Cragoe Jr.; Elizabeth R. Simons

Book ID
115728095
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
502 KB
Volume
903
Category
Article
ISSN
0005-2736

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We have estimated the changes in cytosolic pH (pHi) that occur when human platelets are stimulated by thrombin. Changes in pHi were estimated (i) from the H + effiux across the plasma membrane using an extracellular pH electrode and (ii) using an intracellular pH-sensitive fluorescent dye (BCECF). S