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Three-Residue Turns in α/β-Peptides and Their Application in the Design of Tertiary Structures

✍ Scribed by Gangavaram V. M. Sharma; Pendem Nagendar; Kallaganti V. S. Ramakrishna; Nagula Chandramouli; Madavi Choudhary; Ajit C. Kunwar


Book ID
112005425
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
856 KB
Volume
3
Category
Article
ISSN
1861-4728

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Hybrid Peptides: Expanding the β Turn in
✍ Rajkishor Rai; Prema G. Vasudev; Kuppanna Ananda; Srinivasarao Raghothama; Naray 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 441 KB

## Abstract The β turn segment in designed peptide hairpins has been expanded by the insertion of β‐, γ‐ and δ‐amino acids at the __i__+2 position. The model octapeptides Boc‐Leu‐Phe‐Val‐^D^Pro‐Ac~6~c‐Leu‐Phe‐Val‐OMe (1), Boc‐Leu‐Phe‐Val‐^D^Pro‐β^3^‐Ac~6~c‐Leu‐Phe‐Val‐OMe (2), and Boc‐Leu‐Phe‐Val‐^