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Three Novel Compounds from the Flowers of Bombax malabaricum

✍ Scribed by Jun Wu; Xiao-Hui Zhang; Shu-Wei Zhang; Li-Jiang Xuan

Publisher
John Wiley and Sons
Year
2008
Tongue
German
Weight
241 KB
Volume
91
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Two unusual 9′‐norneolignans, bombasin (1) and bombasin 4‐O‐β‐glucoside (2), and a novel D‐gulono‐γ‐lactone derivative, bombalin (3), were isolated from the flowers of Bombax malabaricum, together with the three known compounds dihydrodehydrodiconiferyl alcohol 4‐O‐β‐D‐glucopyranoside (4), trans‐3‐(p‐coumaroyl)quinic acid (5), and neochlorogenic acid (6). Their structures were elucidated by extensive spectroscopic methods as well as chemical transformation. Compounds 1–3 were evaluated against the HGC‐27 gastrointestinal and Hela cervical human cancer cell lines, but all were inactive in both lines (IC~50~>50β€…ΞΌM).

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