Three new steroidal saponins from the rhizome of Paris polyphylla

✍ Scribed by Yu Zhao; Li-Ping Kang; Yi-Xun Liu; Yang Zhao; Cheng-Qi Xiong; Bai-Ping Ma; Fang-Ting Dong

• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 184 KB
• Volume: 45
• Category: Article
• ISSN: 0749-1581
• DOI: 10.1002/mrc.2039

✦ Synopsis

Abstract

A mixture of a pair of stereoisomeric new spirostanol saponins (1a and 1b) and a new cholestane saponin (2) were isolated from the rhizome of Paris pollyphylla Smith var. yunnanensis. Their structures were elucidated as (25__R__)‐spirost‐5‐en‐3β, 7β‐diol‐3‐O‐α‐L‐arabinofuranosyl‐(1 → 4)‐[α‐L‐rhamnopyranosyl‐(1 → 2)]‐β‐D‐glucopyranoside (1a), (25__R__)‐spirost‐5‐en‐3β, 7α‐diol‐3‐O‐α‐L‐arabinofuranosyl‐(1 → 4)‐[α‐L‐rhamnopyranosyl‐(1 → 2)]‐β‐D‐glucopyranoside (1b) and 26‐O‐β‐D‐glucopyranosyl‐(25__R__)‐Δ^5(6), 17(20)^‐dien‐16, 22‐dione‐cholestan‐3β, 26‐diol‐3‐O‐α‐L‐arabinofuranosyl‐(1 → 4)‐[α‐L‐rhamnopyranosyl‐(1 → 2)]‐β‐D‐glucopyranoside (2) by a combination of HR‐ESI‐MS, FAB‐MS, 1D and 2D NMR techniques (including ^1^H‐NMR, ^13^C‐NMR, ^1^H^1^H COSY, HSQC, HMBC and NOESY). Copyright © 2007 John Wiley & Sons, Ltd.