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Three New Pyridoacridine Type Alkaloids from a Singaporean Ascidian

✍ Scribed by Nilar, ; Sidebottom, Philip J.; Carté, Brad K.; Butler, Mark S.

Book ID
126995431
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
70 KB
Volume
65
Category
Article
ISSN
0163-3864

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✍ Yunjiang Feng; Rohan A. Davis; Melissa L. Sykes; Vicky M. Avery; Anthony R. Carr 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 193 KB

Bioassay-guided fractionation of the crude CH 2 Cl 2 /MeOH extract from the Australian ascidian Polysyncraton echinatum led to the isolation of a new pyridoacridine alkaloid, 12-deoxyascididemin (1), along with two known analogues, ascididemin (2) and eilatin (3). The structure of 1 was determined f