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Three New Phenylpropanoids from Inula nervosaWall.

✍ Scribed by Lan Yan; Ying Huang; Jian-Jun Fu; Jiang-Jiang Qin; Qi Zeng; Yan Zhu; Shi Kai Yan; Wei-Dong Zhang; Hui-Zi Jin

Publisher
John Wiley and Sons
Year
2010
Tongue
German
Weight
147 KB
Volume
93
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Three new phenylpropanoid compounds, named nervolans A–C (1–3, resp.), together with two other known phenylpropanoids, coniferyl diangelate and sinapyl diangelate, were isolated from the aerial parts of Inula nervosa Wall. (Asteraceae), a traditional Chinese medicinal plant. The structures of 1–3 were elucidated by detailed spectroscopic analyses, including HR‐ESI‐MS data and 2D‐NMR spectroscopy. Compounds 1–5 exhibited mild inhibitory effects against NO production in LPS‐stimulated RAW264.7 cells.

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