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Three new MHC haplotypes in broiler breeder chickens

✍ Scribed by E. J. Livant; D. Zheng; L. W. Johnson; W. Shi; S. J. Ewald

Book ID: 104457399
Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 323 KB
Volume: 32
Category: Article
ISSN: 0268-9146
DOI: 10.1046/j.1365-2052.2001.00741.x

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✦ Synopsis

Six distinct serotypes of the chicken B blood group system (which encodes the major histocompatibility complex) were identified in a commercial broiler breeder line (Line C). The B serotypes were compared by B‐G restriction fragment length polymorphism (RFLP) analysis, allele‐specific PCR typing test for B‐LBII family genes and nucleotide sequence analysis of expressed B‐F and B‐LBII family genes. The results indicated the existence of seven distinct B haplotypes. Nucleotide sequence analysis demonstrated that three of the Line C haplotypes encode new B‐F and B‐LB alleles.

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