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Three New Isoprenylated 2-Arylbenzofurans from Artocarpus petelotii

✍ Scribed by Lei Chen; Ai-Jun Hou

Publisher
John Wiley and Sons
Year
2005
Tongue
German
Weight
85 KB
Volume
88
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Three new isoprenylated 2‐arylbenzofurans, artopetelins A–C (1–3), were isolated as minor constituents from the EtOH extract of the root barks of Artocarpus petelotii Gagnep. Their structures were elucidated by spectroscopic methods, including HR‐EI‐MS and 2D‐NMR techniques.

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The structures were elucidated by spectroscopic methods. Norartocarpin (3), cudraflavone C (5), brosimone I (8), artotonkin (11), albanin A (13), and artopetelin M ( 14) showed inhibitory effects on pancreatic lipase with IC 50 values ranging from 1.8 AE 0.1 to 63.8 AE 3.6 mm.