Novel 2-Arylbenzofuran Derivatives from Artocarpus petelotii
β Scribed by Lei Chen; Wei Jiang; Ai-Jun Hou
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- German
- Weight
- 132 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0018-019X
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β¦ Synopsis
Abstract
Further phytochemical investigations on the root barks of Artocarpus petelotii Gagnep afforded four novel isoprenylated 2βarylbenzofuran derivatives, namely artopetelins DβG (1β4). Their structures were elucidated by spectroscopic methods, mainly by 2DβNMR techniques. The biogenetic origins of artopetelins F and G (3 and 4) were also postulated.
π SIMILAR VOLUMES
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## Abstract Three new isoprenylated 2βarylbenzofurans, artopetelins AβC (**1**β**3**), were isolated as minor constituents from the EtOH extract of the root barks of __Artocarpus petelotii__ Gagnep. Their structures were elucidated by spectroscopic methods, including HRβEIβMS and 2DβNMR techniques.
The structures were elucidated by spectroscopic methods. Norartocarpin (3), cudraflavone C (5), brosimone I (8), artotonkin (11), albanin A (13), and artopetelin M ( 14) showed inhibitory effects on pancreatic lipase with IC 50 values ranging from 1.8 AE 0.1 to 63.8 AE 3.6 mm.