✦ LIBER ✦

Three missense mutations in arg codons of the factor viii genes of mild to moderately severe hemophilia a patients

✍ Scribed by A.P. Reiner; S.M. Stray; A.R. Thompson

Book ID: 119038677
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 628 KB
Volume: 66
Category: Article
ISSN: 0049-3848
DOI: 10.1016/0049-3848(92)90159-8

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Identification of a missense mutation in

Identification of a missense mutation in the factor VIII gene of a mild hemophiliac

✍ Gitschier, J; Wood, W.; Shuman, M.; Lawn, R. 📂 Article 📅 1986 🏛 American Association for the Advancement of Scienc 🌐 English ⚖ 628 KB

Mutations of the factor VIII gene in Tha

Mutations of the factor VIII gene in Thai hemophilia A patients

✍ V. Akkarapatumwong; S. Oranwiroon; P. Pung-amritt; A. Treesucon; P. Thanootaraku 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 121 KB 👁 2 views

Hemophilia A is a common X-linked bleeding disorder caused by mutations in the coagulation factor VIII gene. The entire coding and essential sequences of the factor VIII gene were generated by a combination of genomic DNA amplification and long reverse transcription-polymerase chain reaction (long R

Mild hemophilia A resulting from Arg-to-

Mild hemophilia A resulting from Arg-to-Leu substitution in exon 26 of the factor VIII gene

✍ Hiroshi Inaba; Michio Fujimaki; Haig H. Kazazian; Stylianos E. Antonarakis 📂 Article 📅 1989 🏛 Springer 🌐 English ⚖ 508 KB

Intensive peri-operative use of factor V

Intensive peri-operative use of factor VIII and the Arg593→Cys mutation are risk factors for inhibitor development in mild/moderate hemophilia A

✍ C.L. ECKHARDT; L.A. MENKE; C.H. VAN OMMEN; J.H. VAN DER LEE; R.B. GESKUS; P.W. K 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 143 KB

Inversions of the Factor VIII Gene in Ja

Inversions of the Factor VIII Gene in Japanese Patients with Severe Hemophilia A

✍ Kazuyoshi Fukuda; Hiroyuki Naka; Shogo Morichika; Masaru Shibata; Ichiro Tanaka; 📂 Article 📅 2004 🏛 Carden Jennings Publishing 🌐 English ⚖ 155 KB

Amino acid substitutions in conserved do

Amino acid substitutions in conserved domains of factor VIII and related proteins: Study of patients with mild and moderately severe hemophilia A

✍ Carol Diamond; Scott Kogan; Barbara Levinson; Jane Gitschier 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 863 KB

Mutations leading to hemophilia A by substitution of amino acids in coagulation factor VIII may provide important clues to the structure and function of this large and enigmatic protein. To efficiently find missense mutations, hemophiliacs with mild and moderately severe forms of the disease were su