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Inversions of the Factor VIII Gene in Japanese Patients with Severe Hemophilia A

✍ Scribed by Kazuyoshi Fukuda; Hiroyuki Naka; Shogo Morichika; Masaru Shibata; Ichiro Tanaka; Midori Shima; Akira Yoshioka


Book ID
111835301
Publisher
Carden Jennings Publishing
Year
2004
Tongue
English
Weight
155 KB
Volume
79
Category
Article
ISSN
0925-5710

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✍ Weinmann, Ann F.; Schoof, Jon M.; Thompson, Arthur R. πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 700 KB

Inversions between a gene A copy within intron 22 of the factor Vlll gene and additlonal copies outside the factor Vlll gene were found In 49 families with hemophilia A. Inversion patterns were that of recombination with a distal gene A copy in 34, a proximal copy In 14, and a third (variant) copy i