For safe autografts with peripheral blood hematopoietic cells (PBSCT), better methods for determining the kinetics of stem cell populations and predicting engraftment speed after PBSCT need to be established. Current methods include culture in semi-solid medium and measurement of CD34 cell surface a
Three-hour collection of committed and multipotent hematopoietic progenitor cells by apheresis
β Scribed by L. C. Lasky; J. A. Smith; J. Mccullough; E. D. Zanjani
- Book ID
- 114438455
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 259 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0372-1248
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Peripheral blood progenitor cells (PBPC) have been extensively used to restore hematopoiesis after myeloablative chemotherapy. While collection regimens designed for optimal mobilization of PBPC are becoming standardized, the ideal venous access option for collection remains unresolved. The purpose
Different models have been proposed to explain lineage commitment in hemopoiesis. Some suggest that lineage commitment occurs in a stochastic manner without the direct influence of extracellular factors; others postulate that cytokines determine whether multipotent cells will become erythroid or gra
We retrospectively investigated the feasibility of the apheresis procedure for red blood cell (RBC) reduction with a closed-bag system. We also sought to determine the optimal processing volume for the maximal recovery of hematopoietic progenitor cells (HPC). Twelve bone marrow (BM) harvests were pr