Chemical synthesis, characterization and
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Nicola F. Dawson; David J. Craik; Ailsa M. Mcmanus; Stuart G. Dashper; Eric C. R
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Article
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2000
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John Wiley and Sons
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English
⚖ 141 KB
The 32-residue peptide, RK-1, a novel kidney-derived three disulfide-bonded member of the antimicrobial h-defensin family, was synthesized by the continuous flow Fmoc-solid phase method. The crude, cleaved and S-reduced linear peptide was both efficiently folded and oxidized in an acidic solution of