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Three-dimensional quantitative structure–activity relationship study on paullones as CDK inhibitors using CoMSIA and CoMFA

✍ Scribed by Lili Zhu; Tingjun Hou; Xiaojie Xu


Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
161 KB
Volume
7
Category
Article
ISSN
1610-2940

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## Abstract The three‐dimensional quantitative structure‐activity relationships of a series of 5‐[1‐aryl‐1,4‐dihydro‐6‐methylpyridazin‐4‐one‐3‐yl]‐2‐arylamino‐1,3,4‐thiadiazoles, related to the fungicidal activity, were studied using the comparative molecular field analysis (CoMFA). The results sho