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Quantitative Structure-Activity Relationships of Phenyltropanes as Inhibitors of Three Monoamine Transporters: Classical and CoMFA studies

โœ Scribed by Muszynski, Inge C. ;Scapozza, Leonardo ;Kovar, Karl-Artur ;Folkers, Gerd


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
255 KB
Volume
18
Category
Article
ISSN
1611-020X

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3D-Quantitative Structure Activity Relat
โœ Muegge, Ingo ;Podlogar, Brent L. ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 182 KB ๐Ÿ‘ 1 views

A series of CoMFA models have been derived from docking-based and atom-based alignments. The statistics of these approaches has been compared to determine whether a docking approach can be employed as an automated alignment tool for the development of 3D-QSAR models. Using a well-characterized train