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Three Cyclized Isoprenylated Flavonoids from the Roots and Rhizomes of Sophora tonkinensis

✍ Scribed by Peilan Ding; Daofeng Chen


Publisher
John Wiley and Sons
Year
2007
Tongue
German
Weight
227 KB
Volume
90
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Two new flavanones, tonkinochromanes D (1) and E (2), and a new chalcone, tonkinochromane F (3), were isolated from the roots and rhizomes of Sophora tonkinensis. Their structures were elucidated by spectroscopic methods, including 2D‐NMR and circular‐dichroism (CD) techniques, in combination with HR‐MS analysis. Compounds 13, as well the previously reported tonkinochromanes A–C, were shown by LC‐MS analysis to be ‘artifacts’ resulting from acid‐catalyzed electrophilic cyclization of isoprenyl side chains during extraction.


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✍ Peilan Ding; Daofeng Chen; Kenneth F. Bastow; Alexander K. Nyarko; Xihong Wang; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 German ⚖ 135 KB

## Abstract Three new flavonoids, which are isoprenylated by fused 2,2‐dimethyl‐3,4‐dihydro‐2__H__‐pyran moieties, were isolated from the roots of __Sophora flavescens__ and named flavenochromanes A–C (**1**–**3**). Their structures were elucidated by spectroscopic methods, including 2D‐NMR techniq