𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Three-component synthesis of substituted β-(trifluoromethyl)pyrroles via Grob cyclization of 1,1,1-trifluoro-3-nitrobut-2-ene with 1,3-dicarbonylic compounds and ammonia or primary amines

✍ Scribed by Vladislav Yu. Korotaev; Alexey Yu. Barkov; Ivan V. Kotovich; Vyacheslav Ya. Sosnovskikh


Book ID
113711648
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
378 KB
Volume
138
Category
Article
ISSN
0022-1139

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


One-Pot Three-Component Catalytic Synthe
✍ Victorio Cadierno; José Gimeno; Noel Nebra 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 328 KB 👁 2 views

## Abstract A simple and highly efficient method for the preparation of fully substituted pyrroles, from readily accessible secondary propargylic alcohols, 1,3‐dicarbonyl compounds and primary amines, has been developed. The one‐pot multicomponent reaction, which is catalysed by the system [Ru(η^3^