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Three-component Synthesis of Substituted 5,5-Dimethyl-2-methylthio-4'-oxospiro(pyrrolin-3,1'-cyclohexadienes) by Spirocyclization of Methoxy-substituted Benzenes

✍ Scribed by V. A. Glushkov; O. G. Ausheva; G. A. Postanogova; Yu. V. Shklyaev


Book ID
110365146
Publisher
Springer US
Year
2000
Tongue
English
Weight
64 KB
Volume
36
Category
Article
ISSN
0009-3122

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Novel synthesis and biological activity
✍ S. G. Badne; D. K. Swamy; V. N. Bhosale; S. V. Kuberkar πŸ“‚ Article πŸ“… 2011 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 183 KB

## Abstract 2‐Amino‐6‐methoxybenzothiazole **1** on reaction with bis(methylthio)methylene malononitrile **2** in the presence of dimethyl formamide and catalytic amount of anhydrous potassium carbonate afforded 3‐cyano‐4‐imino‐8‐methoxy‐4__H__‐pyrimido[2,1‐__b__][1,3]benzothiazole **3**. Under sim