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Three-Component, One-Pot Sequential Synthesis of Tetracyclic Pyrido[2′,1′:2,3]imidazo[5,1-a]isoquinolinium Compounds as Potent Anticancer Agents

✍ Scribed by Huayong Zhou; Wei Wang; Oleg Khorev; Yongliang Zhang; Zehong Miao; Tao Meng; Jingkang Shen


Book ID
115555410
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
1007 KB
Volume
2012
Category
Article
ISSN
1434-193X

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## Abstract An efficient one‐pot synthesis of pyrido[1,2‐__a__]‐fused 1,3‐diazaheterocyclic compounds by three‐component reaction of diamine, nitroketene dithioacetal (=1,1‐bis(methylsulfanyl)‐2‐nitroethene), and electron‐poor itaconic anhydride (=2‐methylidenesuccinic anhydride=2‐methylidenebutane