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Three-Component, One-Pot Sequential Synthesis of Functionalized Cyclazines: 3 H -1,2a 1 ,3-Triazaacenaphthylenes

✍ Scribed by Sun, Hongpeng; Zhou, Huayong; Khorev, Oleg; Jiang, Ruwei; Yu, Ting; Wang, Xin; Du, Yongli; Ma, Yi; Meng, Tao; Shen, Jingkang


Book ID
118044476
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
545 KB
Volume
77
Category
Article
ISSN
0022-3263

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## Abstract The reactive 1 : 1 zwitterionic intermediate formed by the addition of isocyanides to dialkyl acetylenedicarboxylates was trapped with 4‐arylurazoles to produce the highly functionalized pyrazolo[1,2‐__a__][1,2,4]triazoles **5** in good yields (__Table__). The structures of the products