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Three-component domino reaction synthesis of highly functionalized bicyclic pyrrole derivatives

✍ Scribed by Chen, Xue-Bing; Wang, Xiao-Ying; Zhu, Dan-Dan; Yan, Sheng-Jiao; Lin, Jun

Book ID
121669698
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
739 KB
Volume
70
Category
Article
ISSN
0040-4020

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Formation of Highly Substituted Pyrrole Derivatives: An Unexpected Domino Reaction. -If the reaction is performed with 13 C methyl labeled amine (Ia), the carbon atom is found in the benzyl-substituted 3-position of pyrrole (IIIa). On the basis of this result a mechanism is proposed for the reaction