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Thiosemicarbazones derived from 1-indanones as new anti-Trypanosoma cruzi agents

✍ Scribed by María E. Caputto; Lucas E. Fabian; Diego Benítez; Alicia Merlino; Natalia Ríos; Hugo Cerecetto; Graciela Y. Moltrasio; Albertina G. Moglioni; Mercedes González; Liliana M. Finkielsztein

Book ID: 113495490
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 680 KB
Volume: 19
Category: Article
ISSN: 0968-0896
DOI: 10.1016/j.bmc.2011.09.037

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## Abstract magnified image We herein report conventional and microwave‐assisted methods for the synthesis of a series of compounds containing some bivalent ion chelating requirements useful to exert potential HIV‐1 integrase (IN) enzyme inhibition activity. The biological screening highlighted tha