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Thioredoxin secreted upon ultraviolet A irradiation modulates activities of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in human dermal fibroblasts

✍ Scribed by Jang-Hee Oh; An-Sik Chung; Holger Steinbrenner; Helmut Sies; Peter Brenneisen


Book ID
116176907
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
327 KB
Volume
423
Category
Article
ISSN
0003-9861

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## Abstract Fibroblasts, a major constituent of gingival connective tissue, can produce immunoregulatory cytokines and proteolytic enzymes that may contribute to tissue destruction. In this study, we evaluated the production of matrix metalloproteinases (MMPs), tissue inhibitors of MMPs (TIMPs), an