Activation of cell-survival transcriptio
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Martin Reidy; Pius Zihlmann; Jeffrey A. Hubbell; Heike Hall
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Article
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2006
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John Wiley and Sons
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English
⚖ 1009 KB
## Abstract Ligation of the integrin α~v~β~3~ in endothelial cells has been shown to be important for their survival. Such ligation induces signalling events merging into the Raf‐Ras‐ERK cascade that eventually induces activation of nuclear factor kappa B (NFκB), leading to its phosphorylation and