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Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB): a new potential therapeutic target in atherosclerosis?

✍ Scribed by Da̧bek, Józefa (author);Kułach, Andrzej (author);Ga̧sior, Zbigniew (author)

Book ID
122025822
Publisher
Elsevier B.V.
Year
2010
Tongue
English
Weight
131 KB
Volume
62
Category
Article
ISSN
1734-1140

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Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. TGR5 also displays strong attenuation of macrophage reactivity in vitro, but the physiological roles of TGR5 in inflammatory response, and its mechanism, is unk