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Thiophene-2-carbaldehyde and benzaldehyde thiosemicarbazones in reactions with propargyl bromide and 1,3-dibromopropyne

✍ Scribed by V. N. Elokhina; A. S. Nakhmanovich; L. I. Larina; T. I. Yaroshenko; S. V. Amosova

Book ID: 111464931
Publisher: SP MAIK Nauka/Interperiodica
Year: 2009
Tongue: English
Weight: 293 KB
Volume: 45
Category: Article
ISSN: 1070-4280
DOI: 10.1134/s1070428009020122

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## Abstract Isoquinolinones were brominated using __N__‐bromosuccinimide in dimethylformamide at room temperature to give 4‐bromo‐3‐substituted isoquinolin‐1‐(2__H__)‐ones. The reaction of these isoquinolinones with propargyl bromide in the presence of anhydrous potassium carbonate yielded __N__ an