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Thiomuscimol, a new photoaffinity label for the GABAA receptor

โœ Scribed by Mogens Nielsen; Michael-Robin Witt; Bjarke Ebert; Povl Krogsgaard-Larsen

Book ID
113398996
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
317 KB
Volume
289
Category
Article
ISSN
0922-4106

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## Abstract The synthesis of tritium labelled thiomuscimol(5โ€amino[^3^H]~2~methylโ€3โ€isothiazolol) (7c), a specific and highโ€affinity agonist photoaffinity label for GABA~A~ receptors, is described. The synthesis of 7c is based on a procedure for the preparation of 5โ€amino[^2^H]~2~methylโ€3โ€isothiazo