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[3H]Propyl-6-azido-β-carboline-3-carboxylate: a new photoaffinity label for the GABAA-benzodiazepine receptor

✍ Scribed by Jürgen Zezula; Susanne Karall; Robert H. Dodd; Werner Sieghart


Book ID
115890309
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
379 KB
Volume
281
Category
Article
ISSN
0014-2999

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## Abstract The preparation of [^3^H]‐labelled tert‐butyl 8‐chloro‐5,6‐dihydro‐5‐methyl‐6‐oxo‐4H‐imidazo[1,5‐a][1,4]benzodiazepine 3‐carboxylate (TCIB, 6), a high affinity ligands for the diazepam insensitive (DI) subtype of the benzodiazepine receptor (BZR) is described. Synthesis of [^3^H]TCIB wa