Thiolated chitosan: Development and in vivo evaluation of an oral delivery system for leuprolide
✍ Scribed by Javed Iqbal; Gul Shahnaz; Glen Perera; Fabian Hintzen; Federica Sarti; Andreas Bernkop-Schnürch
- Book ID
- 116438533
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- French
- Weight
- 244 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0939-6411
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The aim of this study was the preparation and in vivo evaluation of a nasal insulin delivery system based on thiolated chitosan. 2-Iminothiolane was covalently attached to chitosan. The resulting conjugate (chitosan-TBA) exhibited 304.9 +/- 63.5 micromol thiol groups per gram polymer. Microparticles
The aim of the present study was to investigate the effect of poly(acrylic acid)-cysteine (PAA-cysteine) exhibiting a molecular mass of 100 and 250 kDa and reduced glutathione (GSH) on the absorption of the P-glycoprotein (P-gp) and cytochrome P450 (CYP450) substrate paclitaxel in vitro and in vivo.