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Thiolactomycin inhibits d-aspartate oxidase: A novel approach to probing the active site environment

โœ Scribed by Masumi Katane; Yasuaki Saitoh; Toshihiko Hanai; Masae Sekine; Takemitsu Furuchi; Nobuhiro Koyama; Izumi Nakagome; Hiroshi Tomoda; Shuichi Hirono; Hiroshi Homma


Book ID
116309276
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
947 KB
Volume
92
Category
Article
ISSN
0300-9084

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โœ Mary George Johnson; Duane D. Bronson; Jan E. Gillespie; Donetta S. Gifford-Moor ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 699 KB

A solid phase chemistry approach utilizing Mitsunobu chemistry, amine functionalization, and parallel purification was used to produce a diverse library of benzothiophene analogs. These analogs were used to advance the SAR of this class of molecules and give new directions for future studies.