Thioacetic Acid/NaSH-Mediated Synthesis of N -Protected Amino Thioacids and Their Utility in Peptide Synthesis
β Scribed by Mali, Sachitanand M.; Gopi, Hosahudya N.
- Book ID
- 124061140
- Publisher
- American Chemical Society
- Year
- 2014
- Tongue
- English
- Weight
- 485 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0022-3263
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## Abstract __N__βUrethaneβprotected __N__βcarboxyanhydrides (UNCAs) are very reactives. They have been successfully used in peptide synthesis, in both solution and solid phase. We have demonstrated that UNCAs are interesting starting materials for the synthesis of various amino acid derivatives. C
Using the host-guest technique, tentative scales for the helix-inducing power and the (3-structure-forming potential of various side-chain protected amino acid residues in trifluoroethanol are established mainly by CD measurements. The generally lower tendency for (3-structure formation of the host-