Thiazolidinone-Annulated Pyrrolobenzodiazepines. Synthesis and Properties of a New Ring System.
✍ Scribed by Andreas Schmidt; Abbas Gholipour Shilabin; Martin Nieger
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 13 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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Absfhzct. The optically active tax01 A-ring unit 3 was synthesized in 11 steps from 2-isopropyl-2-propenol. The stereogenic centers were introduced via the asymmeuic glyoxylateene reaction and the Sharpless asymmetric epoxidation reaction. The total synthesis of tax01 (1) and analogous compounds ha
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## Abstract __meso__‐Tetraarylporphyrin complexes (M = Ni, Cu, Zn, H~2~) fused to an imidazole ring across two neighboring β‐pyrrolic positions were synthesized through a cyclization reaction between β,β′‐diaminoporphyrins and formic acid or trimethyl orthoformate under acidic conditions. Two synth