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Pyrimidine-Annulated Pyrrolobenzodiazepines. A New Ring System Related to Aspergillus Alkaloids.

✍ Scribed by Andreas Schmidt; Abbas Gholipour Shilabin; Jan Christoph Namyslo; Martin Nieger; Sascha Hemmen


Publisher
John Wiley and Sons
Year
2005
Weight
17 KB
Volume
36
Category
Article
ISSN
0931-7597

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Pyrimidine Derivatives and Related Compo
✍ Mohamed Helmi Elnagdi; Mohamed Mohamed Mohamed Sallam; Mohamed Ajmal Mohamed Ili πŸ“‚ Article πŸ“… 1975 πŸ› John Wiley and Sons 🌐 German βš– 705 KB

## Abstract 3,5‐Diamino‐4‐phenylazo‐pyrazoles (**1a–1c**) react with acetylacetone and with ethyl acetoacetate to yield the corresponding pyrazolo[1,5‐a]pyrimidine derivatives **2a–2c** and **3a–3c**, respectively. Whereas **1a–1c** add readily to methyl acrylate yielding the 4,5,6,7‐tetrahydropyr