Thiazolidinedione suppresses the expression of erythroid phenotype in erythroleukemia cell line K562
โ Scribed by Nobuhisa Hirase; Toshihiko Yanase; Yi-ming Mu; Koichiro Muta; Tsukuru Umemura; Ryoichi Takayanagi; Hajime Nawata
- Book ID
- 114119746
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 220 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0145-2126
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Cells of the human erythroleukemic line K562 can be manipulated by culture conditions to arrest within the GI phase of the cell cycle and subsequently to enter S phase synchronously after release from G1. Cell cultures subjected to serum deprivation and hydroxyurea (HU) treatment demonstrated less t