Thiamine hydrochloride (VB1): an efficient promoter for the one-pot synthesis of benzo[4,5]imidazo[1,2-a]pyrimidine and [1,2,4]triazolo[1,5-a]pyrimidine derivatives in water medium
✍ Scribed by Liu, Junhua; Lei, Min; Hu, Lihong
- Book ID
- 111647257
- Publisher
- Royal Society of Chemistry
- Year
- 2012
- Tongue
- English
- Weight
- 155 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1463-9262
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📜 SIMILAR VOLUMES
## Abstract **Dedicated to Dr. János Császár on the occasion of his 70^th^ birthday** Ring transformation of 2‐cyanoimido‐3‐methyl‐1,3‐oxazolidine (**10**) yielded 5‐amino‐3‐[__N__‐(2‐hydrox‐yethyl)‐__N__‐methyl]amino‐1__H__‐1,2,4‐triazole (**6**) that was ring closed with different β‐keto esters
Hydrazonoyl bromides 1a-c react with 5-amino-3phenyl-1H-pyrazole, 5-amino-1H-1,2,4-triazole, 2aminopyridine, 2-aminopyrimidine, and 2-aminobenzimidazole to afford the corresponding imidazo[1,2-b]pyrazoles 10, imidazo[1,2-b]-1,2,4-triazoles 11, imidazo[1,2-a]pyridines 16, imidazo[1,2-a]pyrimidines 17