The overexpression, purification and characterization of 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase (HMP kinase) and 4-amino-5-hydroxymethyl-2-methylpyrimidine monophosphate kinase (HMP-P kinase) ate described. Surprisingly HMP-P kinase also shows HMP kinase activity. These enzymes are useful
Thiamine biosynthesis in yeast?evaluation of 4-hydroxy-5-hydroxymethyl-2-methylpyrimidine as a precursor
β Scribed by Baxter, Robert L.; Hartley, A. Bryan; Chan, Henry W. S.
- Book ID
- 111980265
- Publisher
- Royal Society of Chemistry
- Year
- 1990
- Weight
- 524 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1472-7781
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
A series of novel 3-hydroxy-3-(2-imino-3-methyl-5-oxoimidazolidin-4-yl)indolin-2-one analogs (3) have been synthesized under microwave irradiation and conventional heating methods. These analogs were evaluated for in vitro cytotoxicity against a panel of 57 human tumor cell lines. Compound 3o had GI