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Thermodynamics of glutathione binding to the tyrosine 7 to phenylalanine mutant of glutathione S-transferase from Schistosoma japonicum

✍ Scribed by Montserrat Andújar-Sánchez; Josefa Marı́a Clemente-Jiménez; Francisco Javier Las Heras-Vázquez; Felipe Rodrı́guez-Vico; Ana Cámara-Artigas; Vicente Jara-Pérez


Book ID
117314540
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
119 KB
Volume
32
Category
Article
ISSN
0141-8130

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Implications of the ligandin binding sit
✍ Zeyad Yassin; Emilia Ortiz-Salmerón; Federico Garcı́a-Maroto; Carmen Barón; Luis 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 532 KB

The binding interactions between dimeric glutathione transferase from Schistosoma japonicum (Sj26GST) and bromosulfophthalein (BS) or 8-anilino-1-naphthalene sulfonate (ANS) were characterised by fluorescence spectroscopy and isothermal titration calorimetry (ITC). Both ligands inhibit the enzymatic