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Role of mutation Y6F on the binding properties of Schistosoma japonicum glutathione S-transferase

✍ Scribed by Zeyad Yassin; Emilia Ortiz-Salmerón; M.José Clemente-Jiménez; Carmen Barón; Luis Garcı́a-Fuentes

Book ID
117314539
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
155 KB
Volume
32
Category
Article
ISSN
0141-8130

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Implications of the ligandin binding sit
Implications of the ligandin binding site on the binding of non-substrate ligands to Schistosoma japonicum-glutathione transferase
✍ Zeyad Yassin; Emilia Ortiz-Salmerón; Federico Garcı́a-Maroto; Carmen Barón; Luis 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 532 KB

The binding interactions between dimeric glutathione transferase from Schistosoma japonicum (Sj26GST) and bromosulfophthalein (BS) or 8-anilino-1-naphthalene sulfonate (ANS) were characterised by fluorescence spectroscopy and isothermal titration calorimetry (ITC). Both ligands inhibit the enzymatic