Thermodynamic nonideality as a probe of macromolecular isomerizations: Application to the acid expansion of bovine serum albumin

General treatment of competitive binding

General treatment of competitive binding as applied to the potentiometric ion probe technique: Application to the interaction of nonsteroidal anti-inflammatory drugs with bovine serum albumin

✍ Alexandra Th. Angelakou; Evangelos E. Sideris; Georgia N. Valsami; Michael A. Ko 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 610 KB

The binding of naproxen, ketoprofen, phenylbutazone, salicylic acid, azapropazone, and indobufen to bovine serum albumin was studied by applying the potentiometric ion probe technique. An ion-selective electrode for the ion probe 1-anilino-8-naphthalene-sulfonate was utilized for the purposes of thi