Thermodynamic Characterization of the Association of Cholesterol with Phospholipids with Varying Degrees of Unsaturation
โ Scribed by Colville, Marshall J.; Mitchell, Drake C.
- Book ID
- 123113330
- Publisher
- Biophysical Society
- Year
- 2014
- Tongue
- English
- Weight
- 45 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0006-3495
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๐ SIMILAR VOLUMES
A series of C18 and C22 fatty acids, with varying degrees of unsaturation, were tested for their ability to alter the bilayer to hexagonal phase transition temperature of dielaidoylphosphatidylethanolamine. Lowering the pH from 7.4 to 6.4 greatly decreased the bilayer to hexagonal phase transition t
Of the polar lipids studied (phospholipida and glycoiipids), only phosphatidylchohne and sphingomyelin can disperse in water with up to 2 mol cholesteroI/mol polar lipid. However, mixtures of phosphatidylethanolaminamine with small amounts of phosphatidylcholine and mixed lipids from mitochondria an