Thermal regulation of fimA, the Escherichia coli gene coding for the type 1 fimbrial subunit protein
✍ Scribed by Charles J. Dorman; Niamh Ní Bhriain
- Book ID
- 109317889
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 394 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0378-1097
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P1 transduction studies of a mutation of Escherichia coli affecting the rpsB gene previously suggested the map order popC-rpsB-dapD. Biochemical analysis of transductants has now revealed that the rpsB gene lies in fact to the right hand (tsJ) side of the dapD marker.
The fimD gene of Escherichia coli K12 was shown to be necessary for surface localization of type 1 fimbriae, since deletion of the gene resulted in a virtually bald phenotype. The FimD protein was found to be located in the outer membrane. Expressed alone, this protein had a very deleterious effect
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