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Thermal Cyclization of (2-Ethynylphenyl)triazenes: Facile Synthesis of Substituted Cinnolines and Isoindazoles

✍ Scribed by Kimball, David B.; Hayes, Austin G.; Haley, Michael M.


Book ID
115479523
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
31 KB
Volume
2
Category
Article
ISSN
1523-7060

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New substituted 3-amino-5,7,8-trihalo-6-hydroxycinnoline-4-carbonitriles 7 and 8 and the 3-amino-5-chloro-6-hydroxybenzo[h]cinnoline-4-carbonitrile 9 were synthesized in two-steps starting from tetrahalo-1,4-benzoquinones or dichloro-1,4-naphthoquinones, malononitrile and hydrazine.